Publications

Selected Articles:

Chung, C.G., Kwon, M.J., Jeon, K.H., Hyeon, D.Y., Han, M.H., Park, J.H., Cha, I.J., Cho, J.H., Kim, K., Rho, S., Kim, G.R., Jeong, H., Lee, J.W., Kim, T., Kim, K., Kim, K.P., Ehlers, M.D., Hwang, D.*, and Lee, S.B.* (2017)  Golgi outpost synthesis impaired by toxic polyglutamine proteins contributes to dendritic pathology in neurons. Cell Reports 20:356-369. (*: co-corresponding author)


Kwon, M.J., Kim, J.-H., Kim, T., and Lee, S.B. (2017) Pharmacological intervention of early neuropathy in neurodegenerative diseases. Pharmacol. Res. 119:169-177.


Fieni, F., Lee, S.B., Jan, Y.N., and Kirichok, Y. (2012) Activity of the Mitochondrial Ca2+ Uniporter Varies Greatly between Tissues. Nature Communications 3, 1317 doi:10.1038/ncomms2325.


Lee, S.B., Bagley, J.A., Lee, H.Y., Jan, L.Y., and Jan, Y.N. (2011) Polyglutamine proteins cause dendrite defects associated with specific actin cytoskeletal alterations in DrosophilaProc. Natl. Acad. Sci. 108(40):16795-16800.


Rumpf, S.*, Lee, S.B.*, Jan, L.Y., and Jan, Y.N. (2011) Neuronal remodelling and apoptosis require VCP-dependent degradation of the apoptosis inhibitor DIAP1. Development 138(6):1153-60 (*: co-first author)


Lee, S.B.*, Kim, S.*, Lee, J., Park, J., Kim, J.M., and Chung, J. (2007) Atg1, an autophagy regulator, inhibits cell growth by negatively regulating p70 S6 kinase. EMBO reports. 8:360-365. (*:co-first author)


Park, J.*, Lee, S.B.*, Lee, S., Kim, Y., Song, S., Kim, S., Bae, E., Kim, J., Shong, M., Kim, J.M., and Chung, J. (2006) Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkinNature 441:1157-1161.(*:co-first author)



All Published Journal Articles:

Won S.Y., Kim C.Y., Kim, D., Ko, J., Um, J.W., Lee, S.B., Buck M., Kim, E., Heo, W.D., Lee, J.-O., and Kim, H.M. (2017) LAR-RPTP clustering is modulated by competitive binding between synaptic adhesion partners and Heparan Sulfate. Front. Mol. Neurosci. in press.


Chung, C.G., Kwon, M.J., Jeon, K.H., Hyeon, D.Y., Han, M.H., Park, J.H., Cha, I.J., Cho, J.H., Kim, K., Rho, S., Kim, G.R., Jeong, H., Lee, J.W., Kim, T., Kim, K., Kim, K.P., Ehlers, M.D., Hwang, D.*, and Lee, S.B.* (2017)  Golgi outpost synthesis impaired by toxic polyglutamine proteins contributes to dendritic pathology in neurons. Cell Reports 20:356-369. (*: co-corresponding author)


Park, S., Lee, S., Lee, C.-G., Park, G.Y., Hong, H., Lee, J.-S., Kim, Y.M., Lee, S.B., Hwang, D., Choi, Y.S., Fryer J.D., Im, S.-H., Lee, S.-W., and Lee, Y.  (2017) Capicua deficiency causes autoimmunity and promotes follicular helper T cell differentiation via de-repression of ETV5. Nature Communications 8:16037.


Kim, J.-H., Lee, J.H., Lee, I.-S.,  Lee, S.B.*, and Cho, K.S.* (2017) Histone lysine methylation and neurodevelopmental disorders. Int. J. Mol. Sci. 18(7). pii:E1404. doi:10.3390/ijms18071404.  (*: co-corresponding author)

 

Lee, J.H., Kim, J.-H., Kim, S., Cho, K.S.*, and Lee, S.B.* (2017) Chromatin changes associated with neuronal maintenance and their pharmacological application. Current Neuropharmacology doi:10.2174/1570159X15666170601124220 [Epub ahead of print] (*: co-corresponding author)


Jeon, Y.M., Lee, S., Kim, S., Kwon, Y., Chung, C.G., Lee, S., Lee, S.B., and Kim, H.J. (2017) Neuroprotective effects of protein tyrosine phosphatase 1B inhibition against ER stress-induced toxicity. Mol. Cells 40:280-290. 


Woo, H., Ha, S.D., Lee, S.B., Buratowski, S., and Kim, T. (2017) Modulation of gene expression dynamics by co-transcriptional histone methylations. Exp. Mol. Med. 49:e326.


Kwon, M.J., Kim, J.-H., Kim, T., and Lee, S.B. (2017) Pharmacological intervention of early neuropathy in neurodegenerative diseases. Pharmacol. Res. 119:169-177.


Cha, I.J., Lee, J.H., Cho, K.S., and Lee, S.B. (2017) Drosophila tensin plays an essential role in cell migration and planar polarity formation during oogenesis by mediating integrin-dependent extracellular signals to actin organization. Biochem. Biophys. Res. Commun. 484:702-709.


Kweon, J.H., Kim, S., and Lee, S.B. (2017) The cellular basis of dendrite pathology in neurodegenerative diseases. BMB Reports 50:5-11.


Kim, J.H., Lee, B.B., Oh, Y.M., Zhu, C., Steinmetz, L., Lee, Y., Kim, W.K., Lee, S.B., Buratowski, S., and Kim, T. (2016) Modulation of mRNA and IncRNA expression dynamics by the Set2/Rpd3S pathway. Nature Communications 7:13534.

  

Kwon, M.J., Kim, S., Han, M.H., and Lee, S.B. (2016) Epigenetic changes in neurodegenerative diseases. Mol. Cells 39:783-789.


Liu, Q.F., Jeong, H., Lee, J.H., Hong, Y.K., Oh, Y., Kim, Y.-M., Suh, Y.S., Bang, S., Yun, H.S., Lee, K., Cho, S.M., Lee, S.B., Jeon, S., Chin, Y.-W., Koo, B.-S., and Cho, K.S. (2016) Coriandrum sativum suppresses AB42-induced ROS increases, glial cell proliferation, and ERK activation. Am. J. Chin. Med. 44:1325-1347.


Park, B.-O., Kim, S.H., Kong, G.Y., Kim, D.H., Kwon, M.S., Lee, S.U., Kim, M.-O., Cho, S., Lee, S., Lee, H.-J., Han, S.-B., Kwak, Y.S., Lee, S.B.* and Kim, S.* (2016) Selective novel inverse agonists for human GPR43 augment GLP-1 secretion. Eur. J. Pharmacol. 771:1-9. (*: co-corresponding author)


Cho, J.H.*, Park, J.H.*, Chung, C.G., Shim, H.-J., Jeon, K.H., Yu, S.-W., and Lee, S.B. (2015) Parkin-mediated responses against infection and wound involve TSPO-VDAC complex in DrosophilaBiochem. Biophys. Res. Commun.  pii: S0006-291X(15)00901-8. doi: 10.1016/j.bbrc.2015.05.006. (*: co-first author)

 

Kim, H.Y.*, Lee, S.B.*, Kang, H.S., Oh, G.T., and Kim, T. (2014) Two distinct domains of Flo8 activator mediates its role in transcriptional activation and the physical interaction with Mss11.  Biochem. Biophys. Res. Commun. pii: S0006-291X(14)00840-7. doi: 10.1016/j.bbrc.2014.04.161.(*: co-first author)  


Chung, C.G., and Lee, S.B. (2014) Regulation of Mitochondrial Calcium through the MCU complex. KSMCB Webzine 

(http://www.ksmcb.or.kr/file/webzine/2014_05_01.pdf).

 

Lee, S.B.Kang, H.S., and Kim, T. (2013) Nrg1 functions as a global transcriptional repressor of glucose-repressed genes through its direct binding to the specific promoter regions. Biochem. Biophys. Res. Commun. doi:pii: S0006-291X(13)01475-7. 10.1016/j.bbrc.2013.09.015.

Fieni, F., Lee, S.B., Jan, Y.N., and Kirichok, Y. (2012) Activity of the Mitochondrial Ca2+ Uniporter Varies Greatly between Tissues. Nature Communications 3, 1317 doi:10.1038/ncomms2325.


Lee, S.B., Bagley, J.A., Lee, H.Y., Jan, L.Y., and Jan, Y.N. (2011) Polyglutamine proteins cause dendrite defects associated with specific actin cytoskeletal alterations in Drosophila. Proc. Natl. Acad. Sci. 108(40):16795-16800.

 

Rumpf, S.*, Lee, S.B.*, Jan, L.Y., and Jan, Y.N. (2011) Neuronal remodelling and apoptosis require VCP-dependent degradation of the apoptosis inhibitor DIAP1. Development 138(6):1153-60 (*: co-first author)

 

Lee, S.B.*, Kim,W.*, Lee,S.*, and Chung,J. (2007) Loss of LRRK2/PARK8 induces degeneration of dopaminergic neurons in Drosophila. Biochem. Biophys. Res. Commun. 358(2):534-9. Epub 2007 May 4. (*: co-first author)

 

Lee, S.B.*, Kim, S.*, Lee, J., Park, J., Kim, J.M., and Chung, J. (2007) Atg1, an autophagy regulator, inhibits cell growth by negatively regulating p70 S6 kinase. EMBO reports. 8:360-365. (*:co-first author)

 

Park, J.*, Lee, S.B.*, Lee, S., Kim, Y., Song, S., Kim, S., Bae, E., Kim, J., Shong, M., Kim, J.M., and Chung, J. (2006) Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 441:1157-1161.(*:co-first author)

* Comments in Pallanck L, Greenamyre JT. (2006) Neurodegenerative disease: pink, parkin and the brain. Nature 441:1058.

* Selected for F1000 prime: http://f1000.com/prime/1003819

* Related review in Tan JM, Dawson TM. (2006) Parkin blushed by PINK1. Neuron 50: 527-529.

 

Park, J., Kim, S. Y., Cha, G. H., Lee, S.B., Kim, S., and Chung, J. (2005) Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction. Gene 102:133-139

 

Cha, G.H., Kim, S., Park, J., Lee, E., Kim, M., Lee, S.B., Kim, J.M., Chung, J., and Cho, K.S. (2005) Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila. Proc. Natl. Acad. Sci. 102:10345-10350

 

Lee, S.B., Park, J., Jung, J.U., and Chung, J. (2005) Nef induces apoptosis by activating JNK signaling pathway and inhibits NF-kB-dependent immune responses in Drosophila. J. Cell Sci. 118:1851-1859.

 

Kim, T. S., Lee, S.B., Kang, H.S. (2004) Glucose repression of STA1 expression is mediated by the Nrg1 and Sfl1 repressors and the Srb8-11 complex. Mol. Cell. Biol. 24:7695-7706.

 

Cha, G.-H., Cho, K.S., Lee, J.H., Kim, M., Kim, E., Park, J., Lee, S.B., and Chung, J.(2003) Discrete functions of TRAF1 and TRAF2 in Drosophila mediated by JNK- and NF-kB-dependent signaling pathways. Mol. Cell. Biol. 23:7982-7991

 

Lee, S.B.*, Cho, K.S.*, Kim, E., and Chung, J. (2003) blistery encodes Drosophila tensin protein and interacts with integrin and JNK signaling pathway during wing development. Development 130:4001-4010. (*: co-first author)

 

Lee, J.H., Cho, K.S., Lee, J., Kim, D., Lee, S.-B., Yoo, J., Cha, G.-H., and Chung, J. (2002) Drosophila PDZ-GEF, a guaninenucleotide exchange factorfor Rap1 GTPase, reveals a novel upstream regulatory mechanism in the MAP kinase signaling pathway. Mol. Cell. Biol. 22:7658-7666