Alumni

  • In Jun Cha, Ph.D.
  • PhD, 2013-2020

introduce

Education:

Kyungpook National University (B.S.)

Major: Applied bioscience

DGIST (Ph.D.)

Major: Brain & Cognitive Sciences

 

Research Projects:

The role of RNA homeostasis in the nervous system


Publications:

Kim, E.S.*, Chung, C.G.*, Park, J.H.*, Ko, B.S.*, Park, S.S., Kim, Y.H., Cha, I.J., Kim, J., Ha, C.M., Kim, H.J., and Lee, S.B. (2021) C9orf72-associated arginine-rich dipeptide repeats induce RNA-dependent nuclear accumulation of Staufen in neurons. Hum. Mol. Genet. ddab089. doi: 10.1093/hmg/ddab089. (*: co-first author)

Cha, I.J.*, Lee, D.*, Park, S.S., Chung, C.G., Kim, S.Y., Jo,M.G., Kim, S.Y., Lee, B.-H., Lee, Y.-S., and Lee, S.B. (2020) Ataxin-2 dysregulation triggers a compensatory Fragile X mental retardation protein decrease in Drosophila C4da neurons. Mol. Cells 43:870-879. (*: co-first author)

Kim, E.S.*, Chung, C.G.*, Kim, Y.H., Cha, I.J., Park, J.H., Kim, J., Ha, C.M., Kim, H.-J., and Lee,S.B. (2019) C9orf72-associated arginine-rich dipeptide repeats induce RNA-dependent accumulation of Staufen in nucleus. bioRxiv doi: https://doi.org/10.1101/773796. (*: co-first author)

Kwon, M.J.*, Han, M.H.*, Bagley, J.A., Hyeon, D.Y., Ko, B.S., Lee, Y.M., Cha, I.J., Kim, S.Y., Kim, D.Y., Kim, H.M., Hwang, D., Lee, S.B., and Jan, Y.N. (2018) Coiled-coil structure-dependent interactions between polyQ proteins and Foxo lead to dendrite pathology and behavioral defects. Proc. Natl. Acad. Sci. pii: 201807206. doi: 10.1073/pnas.1807206115. (*: co-first author). Recommended in F1000 prime: https://f1000.com/prime/734280121 * Selected as BRIC 한빛사 논문/ 추천논문: http://www.ibric.org/myboard/read.php?Board=hbs_treatise&id=55504&idauthorid=299&ttype=0 * Highlighted in the "In this issue" section: https://doi.org/10.1073/iti4518115

Chung, C.G.*, Kwon, M.J.*, Jeon, K.H.*, Hyeon, D.Y.*, Han, M.H., Park, J.H., Cha, I.J., Cho, J.H., Kim, K., Rho, S., Kim, G.R., Jeong, H., Lee, J.W., Kim, T., Kim, K., Kim, K.P., Ehlers, M.D., Hwang, D., and Lee, S.B. (2017)  Golgi outpost synthesis impaired by toxic polyglutamine proteins contributes to dendritic pathology in neurons. Cell Reports 20:356-369. (*: co-first author) * Recommended in F1000 prime: https://f1000.com/prime/727800724 * Selected as BRIC 한빛사 추천논문: http://www.ibric.org/myboard/read.php?Board=hbs_treatise&id=55474&idauthorid=299&ttype=2

Cha, I.J., Lee, J.H., Cho, K.S., and Lee, S.B. (2017) Drosophila tensin plays an essential role in cell migration and planar polarity formation during oogenesis by mediating integrin-dependent extracellular signals to actin organization. Biochem. Biophys. Res. Commun. 484:702-709.


Thesis title:

Glutamine-rich interactors of mutant huntingtin modulate neuronal toxicity by promoting cytoplasmic huntingtin aggregation