Alumni

  • Myeong Hoon Han, Ph.D.
  • Ph.D. 2015-2021

introduce

introduce

Education:

Konkuk Univ. (B.S.)

Majors: Biological Sciences

DGIST (Ph.D.)

Major: Brain & Cognitive Sciences

 

Research Projects:

Modulation of toxicity from aggregated proteins in neurodegenerative diseases


Publications:

Cho, J.H., Kim, K., Kim, S.A., Park, S., Park, B.-O., Kim, J.-H., Kim, S.-Y., Kwon, M.J., Han, M.H.Lee, S.B., Park, B.C., Park, S.G., Kim, J.-H., and Kim. S. (2020) Deubiquitinase OTUD5 is a positive regulator of mTORC1 and mTORC2 signlaing pathways. Cell Death. Differ. doi: 10.1038/s41418-020-00649-z.

Han, M.H.*, Kwon, M.J.*, Ko, B.S.*, Hyeon, D.Y., Lee, D., Kim, H.-J., Hwang, D., and Lee, S.B. (2020) NF-κB disinhibition contributes to dendrite defects in fly models of neurodegenerative diseases. J. Cell Biol. 219(12):e202004107. doi: 10.1083/jcb.202004107. (*: co-first author).

Kwon, M.J.*, Han, M.H.*, Bagley, J.A., Hyeon, D.Y., Ko, B.S., Lee, Y.M., Cha, I.J., Kim, S.Y., Kim, D.Y., Kim, H.M., Hwang, D., Lee, S.B., and Jan, Y.N. (2018) Coiled-coil structure-dependent interactions between polyQ proteins and Foxo lead to dendrite pathology and behavioral defects. Proc. Natl. Acad. Sci. pii: 201807206. doi: 10.1073/pnas.1807206115. (*: co-first author). Recommended in F1000 prime: https://f1000.com/prime/734280121 * Selected as BRIC 한빛사 논문/ 추천논문: http://www.ibric.org/myboard/read.php?Board=hbs_treatise&id=55504&idauthorid=299&ttype=0 * BRIC 한빛사 interview: http://www.ibric.org/myboard/read.php?Board=tr_interview&id=160229&qinterview=Y * Highlighted in the "In this issue" section: https://doi.org/10.1073/iti4518115

Chung, C.G.*, Kwon, M.J.*, Jeon, K.H.*, Hyeon, D.Y.*, Han, M.H., Park, J.H., Cha, I.J., Cho, J.H., Kim, K., Rho, S., Kim, G.R., Jeong, H., Lee, J.W., Kim, T., Kim, K., Kim, K.P., Ehlers, M.D., Hwang, D., and Lee, S.B. (2017)  Golgi outpost synthesis impaired by toxic polyglutamine proteins contributes to dendritic pathology in neurons. Cell Reports 20:356-369. (*: co-first author) * Recommended in F1000 prime: https://f1000.com/prime/727800724 * Selected as BRIC 한빛사 추천논문: http://www.ibric.org/myboard/read.php?Board=hbs_treatise&id=55474&idauthorid=299&ttype=2

Kwon, M.J., Kim, S., Han, M.H., and Lee, S.B. (2016) Epigenetic changes in neurodegenerative diseases. Mol. Cells 39:783-789.


Honors & Awards:

2021 KBRI Presidential Award at commencement ceremony

2019 8th BCSSS Presentation Award

2018 DGIST BCS 2018 Outstanding Paper Award for Excellence

2018 BRIC 한국을 빛내는 사람들 Interview

2018 KDRC Best Poster Award, Korean Society for Drosophila


Thesis Title:

Disinhibition of NF-kB toxicity leads to dendrite defects in neurodegenerative diseases