Alumni

  • Jeong Hyang Park, Ph.D.
  • PhD, 2013-2021

introduce

Education:

Kyungpook National University (B.S.)

Major: Biotechnology

DGIST (Ph.D.)

Major: Brain & Cognitive Sciences

 

Research Projects:

Changes in nuclear protein translocation in the context of neurodegenerative diseases and aging

 

Publications:

Jang, H.J., Le, M.U.T., Park, J.H., Chung, C.G., Shon, J.G., Lee, G.S., Moon, J.H., Lee, S.B., Choi, J.S., Lee, T.G., and Yoon, S. (2021) Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Phospholipid Changes in a Drosophila Model of Early Amyotrophic Lateral Sclerosis. J. Am. Soc. Mass Spectrom. Doi: 10.1021/jasms.1c00167.

Kim, E.S.*, Chung, C.G.*, Park, J.H.*, Ko, B.S.*, Park, S.S., Kim, Y.H., Cha, I.J., Kim, J., Ha, C.M., Kim, H.J., and Lee, S.B. (2021) C9orf72-associated arginine-rich dipeptide repeats induce RNA-dependent nuclear accumulation of Staufen in neurons. Hum. Mol. Genet. ddab089. doi: 10.1093/hmg/ddab089. (*: co-first author)

Park, J.H.*, Chung, C.G.*, Park, S.S., Lee, D., Kim, K.M., Jeong, Y., Kim, E.S., Cho, J.H., Jeon, Y.-M., Shen, C.J., Kim, H.-J., Hwang, D., and Lee, S.B. (2020) Cytosolic calcium regulates cytoplasmic accumulation of TDP-43 through Calpain-A and Importin a3. eLife 9:e60132. doi: 10.7554/eLife.60132. (*: co-first author).

Chung, C.G.*, Park, S.S.*, Park, J.H.*, and Lee, S.B. (2020) Dysregulated plasma membrane turnover underlying dendritic pathology in neurodegenerative diseases. Front. Cell Neurosci. 14:556461. (*: co-first author)

Park, J.H.*, Chung, C.G.*, Seo, J., Lee, B.H., Lee, Y.S., Kweon, J.H., and Lee, S.B. (2020) C9orf72-Associated Arginine-Rich Dipeptide Repeat Proteins Reduce the Number of Golgi Outposts and Dendritic Branches in Drosophila Neurons. Mol. Cells 43:821-839. Doi: 10.14348/molcells.2020.0130. (*: co-first author)

Kim, E.S.*, Chung, C.G.*, Kim, Y.H., Cha, I.J., Park, J.H., Kim, J., Ha, C.M., Kim, H.-J., and Lee,S.B. (2019) C9orf72-associated arginine-rich dipeptide repeats induce RNA-dependent accumulation of Staufen in nucleus. bioRxiv doi: https://doi.org/10.1101/773796. (*: co-first author)

Jang, H.J., Park, J.H., Lee, G.S., Lee, S.B., Moon, J.H., Choi, J.S., Lee, T.G., and Yoon, S. (2019) Comparison of lipid profiles in head and brain samples of Drosophila Melanogaster using electrospray ionization mass spectrometry (ESI-MS). Mass Spectrometry Letters 10:11.17. 

Le, M.U.T., Son, J.G., Shon, H.K., Park, J.H.Lee, S.B., and Lee, T.G. (2018) Comparison between Thaw-Mounting and Use of Conductive Tape for Sample Preparation in ToF-SIMS Imaging of Lipids in Drosophila miRNA miR-14 model. Biointerphases 13:03B414.

Chung, C.G.*, Kwon, M.J.*, Jeon, K.H.*, Hyeon, D.Y.*, Han, M.H., Park, J.H., Cha, I.J., Cho, J.H., Kim, K., Rho, S., Kim, G.R., Jeong, H., Lee, J.W., Kim, T., Kim, K., Kim, K.P., Ehlers, M.D., Hwang, D., and Lee, S.B. (2017)  Golgi outpost synthesis impaired by toxic polyglutamine proteins contributes to dendritic pathology in neurons. Cell Reports 20:356-369. (*: co-first author) * Recommended in F1000 prime: https://f1000.com/prime/727800724 * Selected as BRIC 한빛사 추천논문: http://www.ibric.org/myboard/read.php?Board=hbs_treatise&id=55474&idauthorid=299&ttype=2

Kim, S.H., Jan, H.J., Park, J.H., Lee, H.J., Kim. J., Yim, Y.-H., Kim, D.B., and Yoon, S. (2017) Comparison of desorption enhancement methods in the low temperature plasma ionization mass spectrometry for detecting fatty acids in Drosophila. Curr. Appl. Phys. 17,1120-1126.

Cho, J.H.*, Park, J.H.*, Chung, C.G., Shim, H.-J., Jeon, K.H., Yu, S.-W., and Lee, S.B. (2015) BBRC pii: S0006-291X(15)00901-8. doi: 10.1016/j.bbrc.2015.05.006 (*: co-first author)


Thesis title:

Characterization of the regulatory mechanism underlying nucleocytoplasmic transport of TDP-43 proteins in neurons